GH3 - A Very Good Book

Nothing I can say about dieting can convince people whose minds are made up. There is a lot of skepticism around these days. There was even more around when GH3 was introduced. I'm reading a good book right now entitled GH3: Will It Keep You Young Longer? by Herbert Bailey. In it he makes the point that there is never acceptance of new theories and new drugs. There is always skepticism. There is even outright ridicule. But no one ridicules people like the American Medical Association. They routinely scorn new developments and consider the status quo the best thing in the world. The truth is they should cast some of that scorn where it belongs. Perhaps they should look at what are touted to be the best diet pills. I guess some people really need to take this in order to loose their weight. For further info, just click the link above.

Synthetic Mesencephalic Enhancer Regulation

In the brain there are certain neurons that talk to one another. Drugs like amphetamine and methamphetamine add noise to the talk by releasing additional neurotransmitters.⁵ But a new class of drugs can increase the volume of such neuronal talk: these substances are called synthetic mesencephalic enhancer regulators.⁴ Exciting new research by J. Knoll and others indicates that it is possible, through "prophylactic administration of a synthetic enhancer substance," to delay the aging of the brain.¹ One such substance is deprenyl.² Another, even stronger enhancer substance, is BPAP. Enhancer substances work in extremely low doses.⁶ (Photo: Professor Joseph Knoll, M.D., Ph.D.)

References

1. Knoll J. Neurochem Res. 2003 Aug; 28(8):1275-97. Enhancer regulation/endogenous and synthetic enhancer compounds: a neurochemical concept of the innate and acquired drives. http://www.ncbi.nlm.nih.gov/pubmed/12834268 (accessed 6/30/09).
2. The enhancer action of deprenyl works at a much lower concentration than that needed for MAO-B inhibition. See, Peter Gaszner, Ildikó Miklya. 2004. “Use of the synthetic enhancer substances (-)-deprenyl and (-)-bpap in major depression.” Neuropsychopharmacologia Hungarica, VI/4; 210-220. http://www.mppt.hu/pdf/0404_KOZL5.pdf (accessed 6/30/09).
3. Knoll, József. 2005. The Brain and Its Self : A Neurochemical Concept of the Innate and Acquired Drives. Berlin and New York: Springer.
4. I. Miklyaa, B. Knolla and J. Knoll. 2003. "A pharmacological analysis elucidating why, in contrast to (-)-deprenyl (selegiline), α-tocopherol was ineffective in the DATATOP study.
   Life Sciences. Volume 72, Issue 23, 25 April, Pages 2641-2648. doi:10.1016/S0024-3205(03)00174-7 (accessed July 1, 2009).
5. Knoll, J. 1998. "(-)Deprenyl (selegiline), a catecholaminergic activity enhancer (CAE) substance acting in the brain." Pharmacology & Toxicology. Vol. 82, No. 2, pp. 57-66.
6. Denes L, Szilágyi G, Gál A, Bori Z, Nagy Z. 2006. Life Sci. Aug 8; 79(11):1034-9. "Cytoprotective effect of two synthetic enhancer substances, (-)-BPAP and (-)-deprenyl, on human brain capillary endothelial cells and rat PC12 cells" http://www.ncbi.nlm.nih.gov/pubmed/16624331 (accessed July 1, 2009).

Advances in Technology

There have been quite a few advances in technology recently and one of them has been in lighting fixtures. There are now quite a few models of lights where all you have to do is touch the base of the light to turn on the lamp. Touch it again and the lamp glows brighter. Again and it increases its illumination even more. Then another touch and the lamp goes off. These are just a few of the discoveries that have added to modern home convenience. But there are also developments in more mundane appliances, such as the so-called simple box cutter. I think we need one like this since we always receive a package. How about you? Check this out today!

Not all the grass is green

John Morgenthaler knows that not all supplements are good. "John was the first to widely announce the dangers of saw palmetto and the possible negative effects of high doses of alpha tocopheral (a vitamin E isomer), beta carotene (a vitamin A), and riboflavin (B2)."¹

References

1. "Smart Publications Author: John Morgenthaler." http://www.smart-publications.com/bios/morgenthaler.php. Accessed 6/9/09.
   

How I Travel in 2009

There are numerous ways to get away from the city. One is to use a bicycle. Another is to use a bus or car. Still another is to go by boat. For my money the best method is boat. This is because I find it the most relaxing. Since I have been studying Buddhism for many years I have learned the value of calming the mind. Not that a boat can always accomplish this, but it often can. Then I watch the sun set and look at the water. Then I call my uncle Theo and ask for auto insurance quotes.

Linguistic Ability Predicts Graceful Aging

Nuns with linguistic ability as young women aged more gracefully than those who couldn't write well.¹

References

1. "A study in the New England Journal of Medicine (1996) looked at 93 elderly nuns and examined the autobiographies they had written 60 years earlier, just as they were joining a convent. The nuns whose essays were complex and dense with ideas remained sharp into their eighties and nineties." "Making Our Minds Last a Lifetime."Katherine Greider, Jill Neimark. Psychology Today. http://www.psychologytoday.com/articles/index.php?term=19961201-000028&page=2. Accessed 6/9/09.
   

Modern Day Robin Hood

A man I consider a modern day Robin Hood is James Kimball. A former tour director and millionaire, he learned through his work on cruise ships that many elderly people were benifittng from a drug that was available in Europe but not in the U.S., deprenyl. He formed a company that manufactured pure deprenyl, much purer that the Eldepryl and other brands now available. Many individuals regained their health through his work. The FDA ran him out of business and sent him to jail for 13 years. But Kimball actually escaped from a minimum security jail in December 2005! He went home to care for his ailing wife and lived for three and a half years under an assumed name and a false identity. This is heroism of the greatest magnitude. His web site said he died but that was a ploy to try to throw federal marshals off the trail. Nevertheless, federal marshals captured him in April 2009 and he is back in prison. In my opinion, and in the opinion of many others, this man should be free today. Putting him in jail was a travesty of justice. His 'crime' was blowing the whistle on the FDA.

References

1. http://www.goodhealthinfo.net/cancer/thirteen_years.htm
2. http://www.usmarshals.gov/news/chron/2009/040809.htm
3. http://mobile.dailycommercial.com/040809escape
   

My New Vacation Plans for 2009

My new vacation plans for 2009 include moving to the Mosquito Coast. There I will construct a series of steel buildings. I will live in one of these windowless buildings while the others are being constructed. The other will have windows. Then I will obtain a copy of Paul Theroux's book The Mosquito Coast. I will read the book by day and by night. I will enjoy a rum and coke. I will make frequent sorties to the river. I will wade through the mud. I will come home changed.

Rare Cancer

The lungs are vulnerable to assault by a variety of toxins. One of these is cigarette smoke. Other toxins include radioactive substances and carbon monoxide. Still another is asbestos. Some people who are exposed to these and other toxic substances become ill. As a result some develop mesothelioma. The treatment options available to such patients range from standard treatment to alternative reatment. Sometimes a mix of both works best.

Selegline in Parkinson's Disease Treatment

Some neurologists still support the use of selegline (deprenyl) early in the treatment of Parkinson's disease.¹ The early promise of neuroprotection from deprenyl may have been illusory, points out a new book, however deprenyl is still prescribed by some doctors for early Parkinson's and it is still an effecive MAO-B inhibitor.²

References

1. Parkinson's Disease: Diagnosis and Clinical Management. Stewart A. Factor, William J. Weiner. Demos Medical Publishing; 2nd edition, 2008; pp. 496-497.
2. Parkinson's disease and movement disorders: diagnosis and treatment guidelines for the practicing physician. Charles H. Adler, J. Eric Ahlskog. Humana Press, 2000; p. 111.