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Wednesday, June 25, 2008

Vitamin E

My husband is always telling me things like, "You don't know vitamin E unless you know tocotrienols. There are eight isomers (or forms) of vitamin E: four tocopherols and four tocotrienols. The American diet is woefully deficient in tocotrienols. Good sources are hard to find in a diet that consists of hamburgers and french fries. You can get tocotrienols from palm oil and other supplements. Swanson makes a great one called Swanson Ultra Full Spectrum E with Tocotrienols. Lester Packer talks about the value of tocotrienols in The Antioxidant Miracle. They're good for the brain and research shows that tocotrienols can reverse -- yes, that's right, reverse -- clogged arteries!"

I hear this morning, noon and night. Little does he know I take vitamin E every day. I don't need a lecture on its chemistry. I take it because it's good for my skin.


WH Leong said...

Dear Ma'am,

Good afternoon.

I'd like to share with you additional information on the more potent member of the Vitamin E family – “Tocotrienols” and their role in the prevention of cardiovascular health diseases (CHD) as well as other free-radical med degenerative diseases.

I am sure that you are aware of the recent 8 clinical trials and studies (Lancet, JAMA, 2001), which negated the health benefit of natural d-alpha-tocopherol and synthetic dl-alpha-tocopherol in the prevention of CHD.

I would like to share with you the latest science on the tocotrienols, which have been proven to be a more potent antioxidant than tocopherol (40-60 times) as well as having additional benefits in reducing cardiovascular risk as proven in human clinical trials such as reversal of arterial blockage and reduction of total serum cholesterol.

Perhaps, we have been looking at the wrong form of Vitamin E - just the tocopherol vitamin E alone. What about the remaining 4 tocotrienol vitamin E - alpha, beta, gamma and delta-tocotrienol? One of the striking facts in those 8 large negative studies with alpha-tocopherol was that they were conducted with a single form of vitamin E – the tocopherol, namely alpha-tocopherol. What is missing in most commercial vitamin E supplements is tocotrienol.

Tocotrienols (T3s) are fat-soluble vitamins related to the family of tocopherols. The term vitamin E is considered to be the generic name describing both the tocopherols and T3s. Tocopherols and T3s are distinguished by their side chain.

While tocopherol has a saturated phytyl tail, T3 possesses an unsaturated isoprenoid side chain.
Tocopherols and T3s are further separated into individual compounds assigned by the Greek letter prefixes (alpha, beta, gamma and delta) depending on the number and position of methyl substitution on the chromanol ring.

While tocopherols are generally present in common vegetable oils (i.e. soy, canola, wheat germ, sunflower), T3s on the other hand, are concentrated in palm oil and rice bran oil. Contrary to the recent news, vitamin E in the form of T3 has been shown in most instances to be beneficial in the prevention of CVD.

I’s like to share the following with you - a concept which is fast gaining popularity in the market :-

Re : E COMPLETE – d-mixed tocopherols + d-mixed tocotrienols – The FULL SPECTRUM VITAMIN E : The Most Complete and Balanced Vitamin E Supplement

Background on “E COMPLETE”
Vitamin E is one of the top-selling supplements in the US. According to the Council of Responsible Nutrition (CRN), about 75% of cardiologists recommend Vitamin E to their patients and 50% of them take Vitamin E themselves. Vitamin E is no doubt the “star-nutrient” of the industry.

There are currently 8 human studies (published in JAMA, NEJM - main stream medical journals) which showed that the regular vitamin E - alpha-tocopherol (natural or synthetic) does not help in lowering the risk of cardiovascular diseases. Instead of just a single form of vitamin E (ie : alpha-tocopherol), consumers are beginning to look for a complete form of vitamin E - mixed tocopherols and mixed tocotrienols as the gamma-tocopherol and tocotrienols have unique health properties which are not shown by the alpha-tocopherol.

All these different forms of vitamin E as produced in nature, works synergistically as a team to confer the maximum benefits associated with vitamin E.

This new vitamin E product concept is getting popular and gaining a lot of attention since the recent negative meta-analysis study on alpha-tocopherol (the regular vitamin E) in the Annals of Internal Medicine (Nov 2004) and JAMA (March 2005) and the Women’s Health Stuyd (WHS), July 2005.

Opinion makers in the industry such as Dr. Andrew Weil, Dr. Stephen Sinatra, Dr. James Balch, Dr. Say Sahelian, Dr. Joseph Mercola in the US have all embraced the need to take a full spectrum vitamin E – with d-mixed tocopherols + d-mixed tocotrienols as a balanced form of vitamin E as nature intends. And it is reflected and proven by recent scientific publications which showed that gamma-tocopherol and obviously tocotrienols have unique health properties within the body and not associated with the regular alpha-tocopherol.

Science of “E COMPLETE”
1) Eight large human clinical trials (Lancet & JAMA, 2001, 2002, 2004 including the latest July 2005 (JAMA) - Women’s Health Study) recently have reported that natural and synthetic alpha-tocopherol alone does not help in reducing the risk of cardiovascular diseases. These studies published in main-stream medical journals reminded us of the 1996 beta-carotene debacle and how consumers are now demanding mixed carotenoid complex now instead of just beta-carotene alone.

2) Research on Vitamin E has progressed to a stage where researchers have identified other forms of vitamin E such as gamma-tocopherol and tocotrienols have unique health properties, which are not associated with the regular alpha-tocopherol. Research scientists and consumers alike are beginning to realize that there is more to Vitamin E than just alpha-tocopherol alone. Please refer to the above for the unique and additional health benefits associated with tocotrienol s but not tocopherol. There are also research publications coming out on the health benefits of gamma-tocopherol.

3) The “E COMPLETE” product concept represents the most complete and most balanced form of Vitamin E supplement in the market. It consists of all the 8 isomers of vitamin E (d-mixed tocopherols and d-mixed tocotrienols) as what produce in nature.

4) There is nothing wrong with taking alpha-tocopherol vitamin E, but one is not getting the maximum benefits Vitamin E can offer. The best vitamin E supplement to take is one that has all the full spectrum vitamin E (d-alpha, beta, gamma and delta-tocopherol and d-alpha, beta, gamma and delta-tocotrienol) as it reflects the latest science on Vitamin E.

5) Only Carotech’s Tocomin® / Tocomax / Tocobeads full spectrum tocotrienol complex provides the all the 4 isomers of tocotrienol - alpha, beta-, gamma and delta-tocotrienol.

For more information on tocotrienol, please visit the educational website :

I believe that it is time for us to spread the message and educate the consumers of the benefits of both the mixed tocopherols and mixed tocotrienol - as the most complete and most balanced form of Vitamin E supplement. This is what produce by nature. I guess nature knows best.

Vitamin E is an orchestra and not a soloist.

Thank you for your time.

WH Leong
Vice President
Carotech Inc
Tel : 732 906 1901

DoN CeSaR said...

MM this is a very important information thanks for sharing it, and a long explanation about this user and the tocotrienol

Jerla Oh lalala said...

hi i was here tc

John Tedder said...

Very interesting blog post and comment from WH Leong. I have cardiovascular disease and I am always interested in finding ways to stop the formation of arterial plaque. I did not know about the tocotrienol side of vitamin E. Thank you.