Steroidogenic acute regulatory protein (StAR) is a . . . protein involved in the transport of cholesterol to the inner mitochondrial membrane and thus plays a key role in steroid biosynthesis. . . . StAR transcripts were abundant in the cerebral cortex, hippocampus, dentate gyrus, olfactory bulb, cerebellar granular layer, and Purkinje cells. Furthermore, other steroidogenic enzymes, side-chain cleavage cytochrome P-450SCC . . . were found to be coexpressed in the hippocampus, dentate gyrus, cerebellar granular layer, and Purkinje cells. These findings strongly indicate that neurosteroids are synthesized in a region-specific manner in the brain.In other words the brain makes chemicals that increase its effective ability to calculate. Like a robot fixing itself, the brain provides itself with neurotransmitters for a wide range of functions, all of which relate to congition and increased mental calculation power.
Reference
- Steroidogenic Acute Regulatory Protein (StAR) Transcripts Constitutively Expressed in the Adult Rat Central Nervous System: Colocalization of StAR, Cytochrome P-450SCC (CYP XIA1), and 3[beta]-Hydroxysteroid Dehydrogenase in the Rat Brain. Molecular Biology. Journal of Neurochemistry. 71(6):2231-2238, December 1998. Furukawa, Aizo; Miyatake, Akira ; Ohnishi, Taira; Ichikawa, Yoshiyuki




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