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Saturday, July 18, 2009

Deprenyl Dosage

There was a time when Dr. Joseph Knoll recommended that people use more and more deprenyl as they aged, but this is apparently no longer the case. In his new book, published in 2005, he recommends that 1 mg per day is all that is necessary. This is because the low dose achieves the "enhancer effect" and it does so without any significant MAO-B inhibition. This, according to Knoll, is the primary mechanism whereby deprenyl achieves its anti-aging effect. The low dose is enough to increase the efficiency of the neurons involved.

  1. Knoll, Joseph. The Brain and Its Self. Springer. 2005.

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